IGF-1 Activates Androgen Receptor Activity

IGF-1

Testosterone is a highly anabolic hormone that acts by binding with androgen receptors. This signals the cell nucleus to augment the synthesis of new proteins. Until recently, scientists and physicians looked at the role of testosterone in muscle metabolism at a very superficial level. They suppose that a normal blood testosterone level meant that the system was functioning normally and even optimally. Advances in cellular biochemistry showed that the system is much more complicated.

Activation of specific genes and hormone receptor sites are more imperative than circulating levels of hormones and chemical growth factors. Besides, hormones such as testosterone, human growth hormone, and IGF-I must work together to make the optimal effect. A Korean study showed that androgen receptors in the gene controlling them were activated best in the presence of IGF-1. IGF-1 is a potent growth factor that works in combination with growth hormone to promote muscle hypertrophy. Intense training can optimize growth hormone and IGF-1 levels, which also assists testosterone metabolism, especially at the receptor level. The study shows that anabolic hormones work together to promote enhancements in muscle growth and strength.
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Nutrients for Cleansing the Heart and Arteries

Heart Cleansing

There are a series of nutrients that decrease cholesterol and saturated fat in the blood and arteries. These are lecithin, vitamin E and vitamin C, and niacin. These nutrients function efficiently in cleaning the arteries when taken in whole food. Lecithin is found in most legumes, particularly in soybeans. Both soybeans and mung beans are recommended by numerous researches and mainly by Chinese medicine for cleansing arteries, although nearly all beans, peas, and lentils are helpful. This is partly because legumes are a good source of choline, a lipotrophic agent that controls fat metabolism; choline is also a main component of lecithin.


When heat symptoms occur with arterial problems, the cooling qualities of soy and mung bean sprouts are useful. These sprouts are usually found in grocery stores and markets with well-stocked produce. Sprouts are also an excellent source of vitamin C, as well as cabbage, parsley, bell peppers, and citrus. Eating the white insides of peppers, the core of cabbage, and a little of the pulp and inner peel of citrus provides bioflavonoids, which act synergetically with vitamin C to strengthen blood vessel walls.

Plant fiber, especially the one found in whole grains, helps to reduce fat in the blood and avoid hardening of the arteries. This is why many people have started to include extra fiber in the diet in the form of bran.

Too much isolated bran, however, can be unhealthy in other respects. Eating the whole grain with all of its fiber and other nutrients intact shows better results than eating the bran alone. Most useful for cleansing the arteries are the grains with a slightly bitter flavor: rye, quinoa, amaranth, and oats, but all other whole grains are useful for this purpose. Unprocessed grains are also an exceptional source of niacin, and they all hold the freshest type of vitamin E in their oils.
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Healing Properties of Fruits: Avocado


AvocadosAvocados have a cooling thermal nature they have a sweet flavor, build the blood and, harmonize the liver, lubricates the lungs and intestines. They are a natural source of lecithin, and are often considered a brain food. More than 80% of its caloric content is easily digested fat, primarily in the form of monounsaturated oils. Persons with cravings for oils but which digest poorly with most fatty foods can usually tolerate avocado. Avocados are rich in copper, which aids in red blood cell formation and it is a nutritious protein source often recommended for nursing mothers. Avocados are also a remedy for ulcers and are known to be effective for women in the skin care procedures.
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Bodybuilding and Cardiovascular Health



Cardiovascular health is very important for bodybuilders and anabolic steroid-using athletes. As we know certain anabolic-androgenic steroids are associated with unfavorable changes in cholesterol, heart attacks and heart failure are some of the most frequent causes of sudden death or serious injuries. Elite bodybuilders and many other anabolic steroids users have suffered heart problems.

The term”Cardiovascular” refers to the heart and the blood vessels. Heart damage is generally caused by ischemia (oxygen deprivation) but can also be electrical in nature, as the heartbeat is generated by an internal conduction system that accelerates and decelerates to meet the circulatory command of the body. When the electrical signal is disrupted, the heart does not beat well or if the disruption is severe enough, may not beat at all. Ischemic damage of the heart s often due to a increase of plaque in the arteries, but may also be due to inappropriate vasoconstriction. Many abusers of cocaine suffered heart attacks due to coronary vasoconstriction, even though their arteries were completely healthy.

Bodybuilding and Cardiovascular Health
When ischemia is mild-to-moderate and long-term, the body grows new blood vessels to cut down the distance between active cells and near capillaries. A person who lives in the mountains likely has a higher capillary density than a person who lives on the beach at sea level. This density is a measure a measure of how branched the circulation is to provide oxygen. Many endurance athletes sleep in individual chambers that copy living in the mountains. This increases their red blood cell supply by stimulating the hormone erythropoietin, and probably excites new blood vessel growth. Many cancer drugs kill tumors by slowing down the blood vessel growth, starving the malignant tumors of oxygen and nutrients.
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Caffeine and Fat Loss

Caffeine

Caffeine is considered by many most effective weight-loss supplement on the market. Not only is it a performance enhancer, but it also speeds up the rate at which fat is broken down within the body, which will assist you burn a higher percentage of calories from fat during workout. If your body draws on fat stores rather than glucose stores while you're working out, your glucose levels stay stable, which means you still feel less hungry.

Don't just head down to the local stores, when it comes to caffeine, you must take the right kind, at the right time, in the right amount, with the right blend of corresponding supplements. Caffeine in coffee form is ineffective for fat burning; the other ingredients in coffee get in the way of its performance- enhancing effects. The most effective form of caffeine for weight loss is an herb called guarana. Guarana is a tropical plant found in the Amazon jungle, where native population have used it for hundreds of years. Guarana contains a composite nearly identical to caffeine. Unlike caffeine, which produces an energy surge with a sudden rush and quick drop-off, guarana is not water-soluble and consequently is not too rapidly absorbed. Guarana's caffeine is released more slowly, over a period of hours, producing an energy boost that continues to rise slowly.

You may also find caffeine in weight-loss supplements in the form of guta kola or kola nut. They are also effective, but guarana is ideal. Caffeine is most effective in fat burning when it is combined with white willow bark. This mixture synergetically elevates energy expenditure by interfering with prostaglandin production and inhibiting norepinephrine fail.
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Train Your Lungs


Running. When you're out on the cardio trail, 80% of the work is done by your diaphragm. Several reasearches demonstrated that strengthening your diaphragm improves your breathing and your endurance. To exercise your diaphragm, it is advisable to practice coordinated breathing. Start by breathing in for two steps and breathe out for the next two. Advance to three-three, then finally four-four.

Lungs Training

Swimming. Breathing in less water is a good place to start and fewer breaths will get you from end to end quicker. Studies at the A study found that swimmers who decrease the frequency of their breaths improve the delivery of oxygen to their muscles. Build up your lung power by increasing the number of strokes per breath, until you can finally manage eight strokes.

Lungs Training

Cycling. Many professional cyclers have a lung capacity of eight litres, which is two litres above average. Although this in part depends on genetics, you can train yourself to be more efficient. Use a weightlifting technique of long, slow exhalation when doing endurance work. Because cycling is basically one long push, inhaling fast and deep prior to slowly breathing out when lifting copies the demands on your muscles and lungs when cycling.

Lungs Training

Soccer. It is important how fast your lungs swap carbon dioxide for oxygen and how fast blood delivers that oxygen to your muscles. The upper level at which training can be sustained for prolonged periods is known as the anaerobic threshold and in Premiership footballers this has been measured at a massive 77%. Improve your breathing Performing soccer activities, but warm-up thoroughly first.

Lungs Training
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