Children's Vitamin D Deficiency is Common

A survey done is 2001-2004 measured the levels of vitamin D in children across America and led to the conclusion that vitamin D deficiency is widespread in the US. Lack of vitamin D is most likely caused by insufficient sun exposure. It is recommended to eat more fish and drink more milk and most importantly, to spend 15-20 minutes a day in the sun. Daily consumption of vitamin D supplements should be considered, especially for high-risk children.

vitamin d deficiency

Lack of Vitamin D Implications

Vitamin D is a global name for a group of fat-soluble prohormones. The main form of vitamin D is D3 which is produced in the skin as a consequence of direct sunlight exposure. The active form of vitamin D influences a lot of organ systems but its major role is maintaining the amount of calcium in the blood.

Vitamin D deficiency is transduced into distorted bone shape and thickness. In children it can lead to rickets, a softening of the bones, and in adults it might contribute to osteoporosis. Vitamin D signals several organs and may lead to the development of cardiovascular diseases.

It has been observed that children with vitamin deficiency had higher blood pressure and lower levels of calcium and good cholesterol in the blood. This observation emphasizes the importance of vitamin D for calcium uptake and prevention of CVD.

Vitamin D Deficiency is Common among US Children

The researchers, headed by Dr. Michal Melamed from the Albert Einstein College of Medicine of Yeshiva University, have analyzed data regarding more than 6,000 children to study vitamin D deficiency frequency in the US. The data used was collected by the National Health and Nutrition Examination Survey 2001-2004. In the survey vitamin D levels of children in the ages of 1-21 years were gathered.

While normal levels of circulating vitamin D are above 30 ng/mL, vitamin D insufficiency is defined as 15-29 ng/mL and a vitamin D deficient person will have less than 15 ng/mL circulating vitamin D. The research showed that the prevalence of both vitamin D insufficiency and deficiency is higher than thought.

According to the survey, 9% of the US children are vitamin D deficient and another 61 percent have insufficient levels of vitamin D. All together, there are more than 58 million children in the US who lack vitamin D. The researchers also found a connection between several genetic and environmental factors and lack of vitamin D.

According to the survey some children are more likely to develop vitamin D insufficiency than others. This group includes both children with a specific genetic background like African-American and Mexican-American children and children that live in cold places, older, obese, spend more than four hours a day in front of a television or a computer or drink less than a cup of milk a week.

They also found that women are more likely to be vitamin D insufficient.


These perturbing outcomes of the research call for immediate actions by both medical staff and parents.

Vitamin D Supplement Should be Consumed

Lack of vitamin D might influence bone health and lead to cardiovascular diseases (CVD). The researchers suggested that vitamin D levels should be checked regularly, especially in high-risk children. They also suggested some ways to increase vitamin D levels.

The most effective way to increase vitamin D levels is to produce it by direct sunlight exposure. An exposure of 15-20 minutes on a daily basis is recommended. Another way to gain vitamin D is from food. Vitamin D can be absorbed from foods such as fish and eggs in its natural form or from milk, cereal and other processed foods which are fortified with vitamin D.

The most convenient and safe way to get vitamin D is through supplements. In many cases sunlight is not strong enough or not enough skin is exposed to it and too little vitamin D is produced. The best way to ensure you and your children get enough vitamin D is taking supplements on a daily basis. The research showed that taking a supplement can help in preventing the deficiency although only 4% of the children took it on a daily basis.

This massive survey confronted everyone with the prevalence of vitamin D deficiency among the children of the United States. Lack of this essential vitamin can cause systematic illness. Some critical steps should be taken by both pediatrics and parents in order to reverse this trend.

buy steroids winstrol

read more →

Chronic Anxiety Unreality Symptoms

chronic anxiety

These sensations, referred to as "depersonalization" and "derealization," are not actual delusions or hallucinations but are rather unpleasant feelings that give the one experiencing them a feeling that reality has been altered. While this symptom-phenomenon can be very unpleasant, it does not indicate psychosis or the onset of developing insanity. These type anxiety symptoms are experienced commonly and in the vast majority of cases, are neither harmful nor dangerous.

The Anxiety Mechanism

Anxiety researchers believe that unreality symptoms occur due to the anxiety mechanism called the “fight-or-flight response.” Part of its purpose is to increase a person’s concentration as it is directed toward a danger or an important task at hand that requires focus and readiness for responding to.

In the process of this, the fight-or-flight response can also cause a person’s self and surroundings to fall into the background so that this increased concentration on an immediate need can occur as-necessary. With anxiety “disorder,” this response begins to occur at inappropriate times or with more frequency than normal, resulting in an unpleasant perception of these symptoms.

A Vicious Cycle

When sensations of unreality occur with anxiety disorders, the focus can be on the anxiety itself that begins to be perceived as a threat or danger in the body. Fearing unpleasant anxiety responses and panic attacks can begin to serve as a “trigger” for unreality symptoms or what is also referred to as a “phobia.” This can become a vicious cycle when anxiety triggers more anxiety but with treatment, chronic anxiety can be significantly diminished and in some cases overcome completely.

Unreality Symptoms

Anxiety suffers vary in symptom manifestations but there are common sensations, feelings and perceptions often described by them as related to depersonalization and derealization. These symptoms can include the following:

Depersonalization:
  • feeling unreal, like a cardboard figure or a robot
  • the sensation that one is watching their own actions from outside of their body
  • feeling as if others are real but they are not
  • lacking recognition of oneself when looking into a mirror reflection
Derealization:
  • feeling as if one’s surroundings have become unreal
  • the sensation that things are being looked at through a veil or a fog
  • feeling as if the surrounding world is a dream or hallucination
  • having momentary doubts about strongly-held beliefs
As mentioned previously, these types of unreality sensations do not represent true mental illness when they are triggered by chronic anxiety (neurosis). They are better categorized as “emotional disorder related symptoms” and a fact stated by many reputable psychiatric professionals and mental health research groups.

When true psychosis develops, a person is typically not aware of it and often, it does not present a concern to them. With anxiety disorder sufferers, it is just the opposite and they are finely tuned-in to all of their emotional and physical sensations.

Treatments

To treat unreality symptoms, the underlying anxiety disorder must be treated. All of the different types of anxiety disorders have potential to cause depersonalization and/or derealization. Cognitive Behavioral Therapy has proven to be highly successful in the treatment of anxiety disorders and symptoms. Exposure therapies, meaning those that help anxiety sufferers to slowly overcome phobias that trigger anxiety responses by gradually increasing their exposure to them has also proven to be a successful treatment.

Anti-anxiety medications and antidepressants can also benefit patients with anxiety disorders and some patients are treated with a combination of psychiatric therapy and medication. It is important that a person suffering anxiety and/or unreality type symptoms see their doctor for thorough evaluation and referral to proper treatment(s).

online steroids canada

read more →

Chlamydia: Our Number One STD Problem

chlamydia

  • Dysuria
  • Painful intercourse
  • Vaginal discharge or itching
  • Rectal pain
  • Pelvic pain

How is Chlamydia Diagnosed?

If the doctor suspects Chlamydia, he/she will obtain
  • History: usually there is history of recent unprotected sex
  • Physical: often penile or vaginal discharge is present
  • Lab tests: either by urine sample or by genital swab, there are accurate tests that can confirm or rule out chlamydia

How is Chlamydia Treated

The primary method of treatment for chlamydia includes appropriate antibiotic treatment. The most common antibiotics prescribed are:
  • Azithromycin
  • Tetracyclines, such as doxycycline
  • Erythromycin
It is critical that all sexual partners be treated, to prevent passing the infection back and forth. A follow-up evaluation may be done in four to six weeks to determine if the infection has been cured.

Prognosis for Chlamydia

Early antibiotic treatment is generally successful and tends to prevent the development of long-term complications. Untreated infection, however, may lead to pelvic or prostatic infections, scarring, and ultimately infertility. If you suspect that you might have Chlamydia, it is highly advisable that you see your physician to get a thorough evaluation.

Prevention of Chlamydia

According to the CDC, the surest way to avoid transmission of STDs is to abstain from sexual contact, or to be in a long-term mutually monogamous relationship with a partner who has been tested and is known to be uninfected.

Latex male condoms, when used consistently and correctly, can reduce the risk of transmission of chlamydia.

CDC recommends yearly chlamydia testing of all sexually active women age 25 or younger, older women with risk factors for chlamydial infections (those who have a new sex partner or multiple sex partners), and all pregnant women. An appropriate sexual risk assessment by a health care provider should always be conducted and may indicate more frequent screening for some women.

buy steroids jakarta

read more →

Clinical Trials – Facts to Consider About New Treatment Options

Clinical trials are biomedical research studies aimed at determining the efficacy, safety levels, and possible side-effects of new medications and therapies. The majority of clinical trials involve testing new medications designed to treat many types of conditions, ranging from auto-immune and blood diseases to cancer. In the case of new medications, the trials are jointly run by pharmaceutical companies, which are responsible of designing the new drugs, and hospitals or health centers, which administer them to patients.

clinical trials

Clinical Trial Facts to Consider Before Enrolling

Most people who consider enrolling for clinical trials do it because existing commercially available drugs and treatments have not succeeded in curing their ailments. Others do it so that doctors and scientists can gather as much information as possible in order to treat diseases. Patients considering participating in clinical trials should analyze several factors, including the mechanisms by which the drugs act, the phase that the clinical trial is in, the inclusion criteria, the potential side effects, and the availability of alternative treatment options, before reaching a decision.

Types of Clinical Trials

According to the US National Institute of Health, there are five types of clinical trials, according to their purpose and treatment options.
  • Treatment Clinical Trials: new drugs, therapies or surgical procedures are tested on patients.
  • Prevention Clinical Trials: new medications, vaccines or vitamins are given to people in order to prevent diseases.
  • Diagnostic Clinicial Trials: involve testing new methods to diagnose diseases or conditions.
  • Screening Clinical Trials: new ways to detect conditions are tested.
  • Quality of Life Clinical Trials: new ways to improve the quality of life for individuals which chronic illnesses are tested.
On the other hand, some clinical trials may involve giving placebos, whether knowingly or unknowingly, to some of the participants. It is important for people considering enrolling in clinical trials to find out whether they could be receiving placebos or new medications.

Phases of Clinical Trials

New medications have to go through five phases of clinical trials before they can be approved by the FDA or corresponding health authority. In total, the development of a new drug can take up to 10 years and pharmaceutical companies usually spend millions of dollars in the process. For this reason, clinical trial protocols have to be carefully planned and followed so that as many external variables can be eliminated while testing the new medications. (Meinert, 1986)
The phases of clinical trials are as follows:
  • Pre-Clinical Studies:This stage involves testing the drugs on lab animals in order to get preliminary information about the new medication’s toxicity, efficacy, and pharmacokinetics, or, in other words, how the body processes and eventually eliminates the drug.
  • Phase 1 Clinical Trials: This is one of the most important stages of clinical trials since it involves the first time a new medication is tested on human beings. Phase 1 clinical trials usually accept between 20 and 100 participants and they are done to determine safe dosage ranges and side effects.
  • Phase 2 Clinical Trials: The new medication is given to a larger group of people (100 to 300) in order to further assess its effectiveness and safety.
  • Phase 3 Clinical Trials: The purpose of phase 3 clinical trials is to confirm a drug’s effectiveness, to monitor its side effects, and to compare it with existing treatment options. It usually involves between 1000 and 3000 participants.
  • Phase 4 Clinical Trials:Also known as post marketing surveillance trial, this stage involves the safety surveillance of a drug after it has been granted permission to be sold in the market. It determines possible interactions of the new medications with other drugs and detects long term side effects.

Benefits of Participating in Clinical Trials

When all treatment options have been explored, some patients can only resort to clinical trials in order to treat their condition. Participants will usually receive expert medical care and their progress will be closely monitored. On the other hand, pharmaceutical companies and hospitals usually agree to provide medications to patients even after they have been accepted by health regulation agencies.

Considering the amount of time and money that the companies spend developing new medications, this means that participants could avoid spending large sums of money on expensive drugs once they are widely available.

Risks of Participating in Clinical Trials

It is clear that people participating in phase 1 clinical trials are subjected to greater risks than those enrolled in later phases. Sometimes unpredictable side effects could appear while new medications are first given to human beings. Since pharmaceutical companies and hospitals need to be very thorough during clinical trials, sometimes they place restrictions on participants. Some are not allowed to eat certain foods or vitamins, travel overseas or have to go to hospital to be routinely monitored. People interested in participating in clinical trials should carefully read the informed consent form to find out about these possible inconveniences.

Benefits And Risks Should be Weighted Before Participating in Clinical Trials

Clinical trials are necessary for the development and release of new medications to the market. Before participating in one, people should analyze the potential benefits and risks involved, as compared to existing treatment options. In the end, participating in a clinical trial can save a patient’s life. On the other hand, depending on particular circumstances, clinical trials can also cause inconveniences or even undesirable side-effects. A very useful site containing information on clinical trials run all over the world is ClinicalTrials.gov, run by the US National Institutes of Health.


Disclaimer: The information contained in this article is for educational purposes only and should not be used for diagnosis or to guide treatment without the opinion of a health professional. Any reader who is concerned about his or her health should contact a doctor for advice.

canadian steroids online

read more →

Cigarette Smoking Causes Addiction: The Debate Ends

cigarette smoking

One in every five deaths in the United States is caused by smoking. The National Institute on Drug Abuse (NIDA) which functions under the U.S. National Institutes of Health (NIH) conservatively estimates that the U.S. economic burden of smoking is $193 billion every year.

Smokers Use Tobacco Because They are Addicted

NIDA puts an end to the age-old controversy whether cigarette smoking is an addiction or not. It says conclusively that most smokers smoke because they are addicted. Nicotine, an ingredient of tobacco causes the addiction. The American Heart Association says that nicotine addiction has remained one of the toughest addictions to break.

There is sufficient research and documented evidence to show that most smokers are aware of the dangers of smoking, and wish to quit the habit. However, over 85% of smokers that try to quit smoking go back to it, most of them within a week.

How Nicotine Works

Research has established that nicotine impacts the brain in numerous ways. NIDA says that the research findings have shown how nicotine triggers reward pathways, which are a part of the nervous system that manages the sense of pleasure. One of the critical brain chemicals associated with the urge to take a drug is dopamine. Research shows that nicotine enhances dopamine levels in the brain.

When such alterations in the brain occur over a prolonged period of time due to persistent exposure to nicotine, it causes addiction. The delivery mechanism of nicotine to the brain is very efficient in the case of cigarette smoking. Nicotine reaches the brain very fast and the level of drug peaks within 10 seconds of smoke inhalation. This property of nicotine adds to its abuse potential.

Withdrawal Symptoms of Smoking

The addictive nature of tobacco is also evident from the fact that the addicts suffer from withdrawal symptoms very quickly once they stop smoking. Most smokers start feeling nervous, anxious, depressed and irritable, and experience an abnormal increase in appetite, disturbed sleep patterns and attention deficit. As a result, most of them feel compelled to go back to cigarettes.

Smoking cessation leads to peaking of the symptoms within the first few days, but there is a gradual reduction in the severity of symptoms with the passage of time. The intensity of withdrawal symptoms varies from one person to another.

New Research Reveals More Addictive Elements

Nicotine may not be the only culprit present in tobacco smoke that causes addiction. Research funded by NIDA reveals that there may be other ingredients too that influence the addictive potential of tobacco. The role of other ingredients in causing addiction is not yet conclusively established, but there are indicators pointing in that direction.

Research conducted on animals by NIDA’s research teams has identified acetaldehyde as another critical chemical found in tobacco smoke that causes an exceptional increase in the reinforcing properties of nicotine. In addition, Acetaldehyde may also be a direct contributor to the addiction of cigarettes.

steroids examples

read more →

Clean Drinking Water

clean drinking water
Our bodies are 70 percent water. If we do not adequately hydrate our bodies they cannot function adequately.

A Cure-All

The water that we drink and consume in food is a carrier, bringing food to our cells and taking away wastes. Making sure that you get plenty of high-quality water every day is one of the most promising routes to digestive wellness. Clean water and good hydration can help prevent many health conditions, from gout, to asthma, and ulcers.

Tap Water

There is more than one good answer about where to find the best drinking water. Tap water can be very polluted because of pollutants that leak into the ground and contaminate the water supply. There is a lot of controversy over the amount of chlorine in tap water. The levels of chlorine needed to kill bacteria are rising due to increasing bacterial resistance, but chlorine has also been strongly associated with higher cancer risks. A simple water filter can efficiently remove chlorine from tap water. Activated charcoal systems are inexpensive and can also remove many pollutants from tap water.

Distilled Water

Distilled water systems and reverse osmosis are two systems recommended by many experts. The downside is that the water distillation process removes all minerals from the water. Because of this, regular consumption of distilled water can lead to a leaching of minerals from the body. Reverse osmosis alone does not kill all microbes, so it may not be protective enough if you are concerned about bacterial contamination.

Ionized Water

Ionized water is the latest on the market. The water is put through micro-filters and then exposed to ultraviolet light, which kills all microbes. The machine can also alkalize water which makes it healthier to drink, ultimately making it less possible for them to become or stay ill.

Bottled Water

Often bottled water is just local, city tap water which has been carefully filtered. If you are buying spring water, make sure to read up in its source and its purity. If you buy water in plastic bottles, you may also be ingesting small amounts of plastic, which have known hormone-disrupting effects. On the plus side, bottled water can be an excellent source of essential minerals.

Using this easy guide, you can determine the best sources of clean, healthy drinking water. Being careful about the water you drink is an essential step to good health. Water is one of the most important substances that the body digests and you should be able to choose the best and healthiest kinds of water for your good health.

buy steroids queensland

read more →