Since Lyme disease is the most common vectored disease in the US, possibly in the world, researchers are studying the organisms intensely. In the US, its causative agent is aspirochete: Borrelia burgdorferi . Borrelia requires both a tick host of the Ixodes genus and a warm-blooded host to complete its infectious cycle , reproducing inside both hosts. These bacteria are transmitted primarily by I. scapularis in the Eastern US, I. pacifica in the Western US. After hatching, ticks pass through three life stages, each lasting about a year: larva, nymph, and adult. Ticks usually feed only once during each life stage. The transfer of Lyme Disease begins when a tick becomes infected by feeding on a vertebrate host with Bb . Inside the tick, the spirochetes are dormant. When the tick feeds on a new host, spirochetes reproduce, are passed to the warm-blooded host, and this host becomes infected. Spirochetes that remain in the tick become dormant again and wait for another feeding bout. Ti
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